The rabbit as an animal model for experimental surgery

• Autor(es):

  Calasans-Maia, Mônica Diuana (Fluminense Federal University. University Hospital Antonio Pedro. Cell Therapy Center);

  Monteiro, Maria Lucia (Fluminense Federal University. School of Veterinary Medicine);

  Áscoli, Fábio Oliveira (Oswaldo Cruz Foundation. Pharmacodynamics Department);

  Granjeiro, José Mauro (Fluminense Federal University. Biology Institute).

• Fonte:

  Acta Cirurgica Brasileira; volume 24, número 4, páginas 325-328. Agosto 2009.

• Assuntos:

  Biocompatible Materials;

  Animal Experimentation;

  Rabbits.

• Resumo:

  The white New Zealand rabbit (Oryctolagus cuniculus) is frequently used as a model for in vivo studies. However, information on precautions when using this animal as an experimental model is limited. This review of the literature covers the gamut from the selection of the animal model all the way to its death, and describes procedures for transporting, raising, breeding, housing, administering anesthesia and handling so as to rationalize the utilization of this species while exploiting its unique characteristics. Based upon the literature and our own experience with white New Zealand rabbits, we conclude that the rabbit is an adequate model for experimental surgery.

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