Dengue and dengue hemorrhagic fever in the State of Pernambuco, 1995-2006

• Autor(es):

  Cordeiro, Marli Tenório (Secretaria de Saúde do Estado de Pernambuco. Laboratório Central de Saúde de Pública, Fundação Oswaldo Cruz. Centro de Pesquisas Aggeu Magalhães. Laboratório de Virologia e Terapia Experimental);

  Schatzmayr, Hermann Gonçalves (Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Virologia. Laboratório de Flavivirus);

  Nogueira, Rita Maria Ribeiro (Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Virologia. Laboratório de Flavivirus);

  Oliveira, Valdete Felix de (Secretaria de Saúde do Estado de Pernambuco. Laboratório Central de Saúde de Pública);

  Melo, Wellinton Tavares de (Secretaria de Saúde do Estado de Pernambuco. Gerência Geral de Vigilância em Saúde);

  Carvalho, Eduardo Freese de (Fundação Oswaldo Cruz. Centro de Pesquisas Aggeu Magalhães. Departamento de Saúde Coletiva).

• Fonte:

  Revista da Sociedade Brasileira de Medicina Tropical; volume 40, número 6, páginas 605-611. Dezembro 2007.

• Assuntos:

  Dengue;

  Dengue virus;

  Dengue hemorrhagic fever;

  Epidemiology.

• Resumo:

  In Pernambuco, the first dengue cases occurred in 1987. After a seven-year interval without autochthonous cases, a new epidemic occurred in 1995. Important aspects of the dengue epidemics during the period 1995-2006 have been analyzed here, using epidemiological, clinical and laboratory data. A total of 378,374 cases were notified, with 612 confirmed cases of dengue hemorrhagic fever and 33 deaths. The mortality rate was 5.4%. The incidence rate increased from 134 to 1,438/100,000 inhabitants, corresponding to the epidemics due to serotypes 2 and 3, in 1995 and 2002, respectively. Dengue mainly affected adults (20-49 years); 40.7% were male and 59.3% were female. From 2003 onwards, the number of cases among individuals younger than 15 years old increased. Out of 225 dengue hemorrhagic fever cases, 42.7% primary and 57.3% secondary infections were identified (p = 0.0279). Neurological manifestations were also observed. From 2002 onwards, serotypes 1, 2 and 3 were circulating; serotype 3 was predominant.

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