Detection of antibodies against hepatitis C virus in a 5 sera pool testing: its use in seroepidemiological survey

• Autor(es):

  Ozaki, Kikumi Suzete (Universidade Federal de Mato Grosso);

  Fontes, Cor Jesus Fernandes (Universidade Federal de Minas Gerais, Universidade Federal de Mato Grosso);

  Fortes, Hildenete Monteiro (Hemocentro Coordenador de Mato Grosso);

  Souto, Francisco José Dutra (Universidade Federal de Mato Grosso).

• Fonte:

  Revista da Sociedade Brasileira de Medicina Tropical; volume 32, número 5, páginas 577-580. Outubro 1999.

• Assuntos:

  Survey;

  Anti-HCV;

  Pool.

• Resumo:

  In order to evaluate the reduction in the cost of testing for antibodies against hepatitis C (EIA) by the pool method, we tested serum samples from a rural population and from patients in a hemodialysis program. Two thirds of the high risk groups were positive. Pooling reduced the reagent use by 80% in the rural population and by 13% in the hemodialysis patients. We conclude that pool testing reduces the cost of anti-HCV detection in low-risk groups.

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